Emma, Norman and Ray are the brightest kids at the Grace Field House orphanage. And under the care of the woman they refer to as “Mom,” all the kids have enjoyed a comfortable life. Good food, clean clothes and the perfect environment to learn—what more could an orphan ask for? One day, though, Emma and Norman uncover the dark truth of the outside world they are forbidden from seeing.

Alcohol, smoking, and stress—in the body subjected to these irritants, the cells responsible for maintaining life seem to fight a war that never ends. Due to a severe shortage of workers, Red Blood Cell AA2153 has to quickly learn to deliver oxygen and collect carbon dioxide, even in dangerous conditions. Meanwhile, White Blood Cell U-1196 has to do her part by dealing with germs and viruses during life-threatening situations. In the midst of these crises, they have to work together to keep the body healthy, despite not knowing if their sacrifices will be worthwhile. Cells at Work! Code Black takes a different approach by showing the grittier side of the jobs our cells perform.